Objective: To explore the possible mechanisms of functional constipation(FC) and Somatic Symptom Disorders (SSD) based on network pharmacology and molecular docking technology, according to the theory of "simultaneous treatment of different diseases". Methods: The effective chemical components of Sinisan Formula and the disease targets of FC and SSD were searched through TCMSP, GeneCards, OMIM and DRUGBANK databases. The bio-informatics website was used to build a Wayne diagram to obtain the common target of drugs and diseases, and the Cytoscape 3.9.1 software was used to draw the "traditional Chinese medicine-common target-disease" network. The DAVID database was used to analyze the common targets of FD and SSD in the treatment of Sinisan Formula, and the GO function analysis and KEGG pathway enrichment analysis were analyzed. Using AutodockTools-1.5.7 for docking, the results were visualized by hydrogenation using the PyMol Stereo3D Quad-buffer (fenzi) software. Results: A total of 137 Sini powder chemical components, corresponding to 239 therapeutic targets, FC5720, SSD8081, and 186 drug components and disease co-targets were obtained. It may involve core targets represented by AKT1 and IL6, and may be related to the regulation of IL-17 signaling pathway, TNF signaling pathway, PI3K-Akt signaling pathway, etc. The results of molecular docking showed that the key active ingredients bound to the core targets and showed a relatively stable conformation. Conclusion: Sinisan Formula plays a role in the "simultaneous treatment of different diseases" through the complex process of multi-component, multi-target, multi-biological process and multi-signaling pathway regulation. This study explains the possible mechanism of the classical formula Sinisan Formula "Different Diseases with the Same Treatment" FC and SSD, and will provide a theoretical basis for in-depth understanding of the mechanism of Sini powder effect and exploring its clinical application in the treatment of FC and SSD.