Objective: To investigate how digestive endoscopy affects upper gastrointestinal bleeding and how that affects prognosis.  Methods: A random number table was used to choose 60 patients with oesophageal or gastric bleeds who were admitted to our hospital between January 2020 and January 2021; 30 patients were assigned to each of the three groups: observation, control, and wait-and-see.  Traditional medical care was used on the control group, whereas intestinal endoscopy was used on the observation group. Clinical results, treatment-related indicators, inflammatory outcomes, and prognostic effects were compared.  Results: When compared to the control group's rate of 58.67 percent, the observation group's rate of clinical efficacy (93.33 percent) was statistically and practically significant.  Time to resolution of faecal occult blood negativity, resolution of hematemesis, and normalisation of stomach tube drainage fluid was significantly shorter in the observation group than in the control group (P<0.05).  The levels of C-reactive protein, tumour necrosis factor alpha, and interleukin-6 in the blood decreased after treatment in both groups, although the decrease in the observation group was significantly greater than in the control group (P<0.05).  The risk of total complications was 23.33 % lower in the observation group than in the control group (P<0.05).  Conclusion: Upper gastrointestinal bleeding can be effectively treated with digestive endoscopy, which also reduces inflammatory response and improves patient prognosis while also improving the patients' clinical symptoms. Widespread clinical use is deserving of it.