The inaugural case of SARS-CoV-2 infection in China in the end of 2019 and the worldwide spread of COVID-19 outbreak leaded to dramatic changes in most of the population dynamics with direct and indirect impact on physical and mental health, particularly with regard to fears and uncertainties in face of the highly contagious disease and the related morbidity and mortality rates, but also in light of the emerging changes within the global economic and financial landscape. In order to contain and mitigate this pandemic, social isolation was instituted, which itself implies significant behavioral adaptations and forced changes in daily routines and therefore constituting a potential study model for relevant areas of human biological and social activity whose clinical impact is important and from which variables of interest with usefulness in individual and public health can be evidenced.