Objective: To examine the effect of anxiety on left heart failure patients with chronic obstructive pulmonary disease (COPD) using a noninvasive ventilator in conjunction with psychopsychogenic therapies. Methods: In total, 110 patients admitted to our hospital with COPD and left heart failure between April 2019 and April 2021 were chosen to participate in this study. Our sample of 55 individuals was divided equally between a control group and a study group using a random number table. In contrast to the control group, which received regular intervention and intervention, the research group received non-invasive ventilation along with psychogenic intervention. Comparisons were made in terms of blood gas indices, lung function indices, mental status, and quality of life. Results: Each group's PaCO2 and PaO2 levels were lower and higher, respectively, after the intervention compared to baseline; In comparison to the control group, the PaCO2 level of the research group was considerably lower, while the PaO2 and SaO2 levels were significantly higher (P<0.05). After the intervention, the LVEF, FEV1/FVC, and PEF levels of both groups increased when compared to their baseline values; however, the research group showed statistically significant gains over the control group on all three measures. Both groups' HAMD and HAMA scores decreased after the intervention compared to pre-intervention levels, with the research group's scores decreasing more than twice as much as the control group's. After the treatments, both groups reported increases in quality of life across the board, although the gains in the latter were more substantial. On all measures of physical and mental health (physical function, physical role, pain level, health status, vitality, social function, emotional role, and mental health), the research group significantly exceeded the control group. Conclusion: In patients with COPD and left heart failure, noninvasive ventilation combined with psychosocial support has been shown to improve blood gas indexes, lung function, emotional well-being, and overall quality of life, making it a promising treatment option.